We create specialty fats & lipids with precision fermentation
At Melt&Marble, we use synthetic biology and metabolic engineering to build proprietary yeast strains.
A key here is iterative engineering cycles and high-throughput screening that help us create and improve yeast cells to produce different fats.
Precision fermentation and microbial bioengineering
We rely on yeasts as our microbial cell factories. Yeast cells consume sugars found in plant sources and produce alcohol from them. Known as fermentation, that is the core technology behind making beer, wine, and bread.
Put simply, we rewire yeast cells to produce the desired fats instead of alcohol.
A closer look at the process
Repurposing Yeast
Yeasts have been used to produce foods and beverages like bread, beer, and wine for thousands of years.
Yeast cells are robust and reliable industrial workhorses. Maybe that’s why biotechnology uses them as the catalysts of choice in industries ranging from bioethanol to insulin production.
Melt&Marble pushes this process one step further by engineering yeasts at the core to produce fats with different properties.
Rewiring metabolism
Metabolism is a network of pathways through which molecules flow. By engineering the metabolism of yeast cells, they can convert natural sugars into fats. Using specialized enzymes, we then dictate the structure and properties of the fats, including chain length and saturation. The result? We can customize fats for specific applications, produce replicas of desired animal and plant fats, and design fats with new properties.
Iterative improvement cycle
We use iterative development cycles to create and test different yeast cell designs. We repeat the cycle until we have robust and high-producing cells with the desired fat profiles.
Check out our toolbox
test
Screening and
characterization
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High-throughput screening
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OMICS
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Controlled bioreactors
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Advanced lipid analytics
build
Synthetic
biology toolbox
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Expression systems
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Pathway control
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Enzyme libraries
design
Rational design and computational tools
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Metabolic modeling
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Bioinformatics
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Target prediction